The Duke's removal from the final remnants of royal life has not only reshaped his future - it's sending ripples through his immediate relatives too.
His ex-wife has now surrendered her ducal status and will simply be known as Sarah Ferguson.
For Sarah, sixty-six, the change will be the most apparent.
Throughout this period, she has maintained the honorary royal divorcee title Sarah, Duchess of York. Currently, she returns to her maiden name of Ferguson.
"She will have lost a certain prestige over this," noted one monarchy expert. "She certainly utilizes the title – even her social media profile is @TheDuchessSarah."
But the loss of her title may impact her much less than the scandal she's facing separately about her own links with the convicted financier.
Last month, several charities dropped her as patron after correspondence from over a decade ago revealed that she called Epstein her "greatest ally" and seemed to apologise for her public criticism of him.
Away from her philanthropy, Ferguson also has various business ventures.
And these, too, are more likely to be impacted by the Epstein scandal than any change in title, says one monarchy analyst.
But Ferguson has been a great survivor in royal circles. She has continued recovering strongly.
"She's the ultimate survivor and master of reinvention," commented one royal author.
For Andrew and Sarah's two daughters, Beatrice, thirty-seven, and Eugenie, 35, there's no formal change.
They continue to be known as princesses, which they have been entitled to since their birth.
Additionally there is no modification to the royal succession order.
Andrew remains eighth position to the throne, followed by his children Beatrice and Eugenie, in ninth and twelfth position in that order.
But in reality their positions are "low down" and will probably become even more remote as years pass.
The princesses are also presently non-official royals, and while they occasionally accept positions – Princess Eugenie was recently announced as a advisor for the King's Foundation network – experts also say they "don't envision a world" in which they would advance into official responsibilities.
"Regarding Beatrice and Eugenie are concerned, I think there's an appreciation of the fact that this controversy isn't about them, and it's not fair for it to impact them directly in the independent lives they are building for themselves," explains one royal commentator.
"Their daughters are most unfortunate affected parties, they've had to suffer in silence and have been dignified in their silence," states another monarchy writer.
Ultimately, there appears to be little doubt that the individual who will be most impacted by these developments will be the Duke himself.
For a man who consistently enjoyed the royal privileges, the pomp and the ceremony, the loss of his titles is profoundly embarrassing.
Therefore lacking those, on a personal level, will significantly count.